Mechanism of Action and Biological Profiling Assays

The SMSSF offers a large variety of mechanism of action assays on lead molecules:

AlphaLisa and AlphaScreen Assays for Biomarkers, Cytokines, Phospho-proteins and more

AKT Phosphorylation
Apoptosis Assays
Cytotoxicity and Cell Proliferation Assays
DNA Damage Assays
ERK1/2 Phosphorylation
HDAC
NFKb
Phosphatase Assays (PP1A and PP2A)

TGF-beta signaling
Tubulin Polymerization
WNT -Beta Catenin (Super Topflash Assay)
Wound Healing and Chamber Migration Assays

Anti-microbial Assays


Custom assay development services are also available.

Contact us for more information!